Trump administration finalizes GLOBE model tying Medicare Part B drug rebates to international prices
The CMS rule narrows the mandatory international price benchmarking model's scope, reducing projected savings versus earlier drafts.
The Pharma Letter · +12 outlets
Trump signs executive order imposing 100% tariff on some imported pharmaceutical drugs
The order adds trade pressure on drugmakers already facing most-favored-nation pricing demands.
Supply Chain Dive · +13 outlets
Zealand Pharma stock slides as Boehringer-partnered obesity drug underwhelms again in phase 3
Boehringer reiterated support for the candidate despite the second disappointing late-stage readout for the partnership.
Fierce Biotech · +1 outlets
Lilly's Foundayo shows heart benefits in diabetes and obesity phase 3 as EASD data rolls out
Deeper phase 3 results for Lilly's oral GLP-1 come as new obesity and diabetes studies dominate the European EASD meeting.
Fierce Pharma · +14 outlets
Pfizer to halt development of closely watched weight-loss drug
The move removes a high-profile oral obesity candidate from Pfizer's pipeline as the GLP-1 field consolidates.
BusinessWorld · +13 outlets
Novo Nordisk signs $2.6B deal with Hengrui for weekly GLP-1/GIP pill
The licensing deal adds a China-origin weekly oral candidate to Novo's obesity pipeline amid intensifying competition.
Healthcare Digital · +5 outlets
FDA approves pirtobrutinib for untreated CLL/SLL without 17p deletion
The label expansion moves the BTK inhibitor into first-line use for a subset of chronic lymphocytic leukemia patients.
AJMC · +10 outlets
FDA grants accelerated approval to BMS's ZENBEXUS for multiple myeloma
The accelerated nod adds a new option in multiple myeloma, a crowded but high-value hematology market.
scanx.trade · +6 outlets
Eli Lilly revenue jumps 47.7% on obesity drug demand as it eyes $2T valuation
Lilly's GLP-1 franchise continues to drive steep growth, with attention on how it reinvests the proceeds, including in China.
Pluang · +1 outlets
Wave Life Sciences says FDA feedback supports registrational pathway for WVE-006 in AATD
A one-year data check could enable faster approval for the RNA editing therapy in alpha-1 antitrypsin deficiency.
Yahoo Finance Australia · +11 outlets
Edwards Lifesciences wins FDA approval for first expandable pediatric heart valve
The device is the first expandable valve cleared for pediatric patients, a small but underserved cardiac segment.
benzinga.com · +9 outlets
Cullinan Therapeutics begins FDA NDA submission for zipalertinib in EGFR exon 20 NSCLC
The filing follows phase 3 REZILIENT3 results for the combo in first-line EGFR exon 20 insertion lung cancer.
Quiver Quantitative · +4 outlets
Kallyope rebrands and raises $94M for migraine trials after Novo obesity deal
The pivot follows a prior obesity partnership with Novo Nordisk, redirecting the company toward neurology.
endpoints.news
Novo Nordisk says obesity drug trial confirms weight loss
The trial result reinforces Novo's GLP-1 portfolio as it defends share against Lilly and new entrants.
BusinessWorld · +14 outlets
Kailera and Hengrui's GLP-1/GIP candidate shows weight and menstrual benefits in PCOS patients
The mid-stage data extends the obesity drug class into a women's health indication beyond weight loss.
BioSpace
Bristol Myers Squibb ends Cellares partnership over Breyanzi manufacturing tech
The split affects cell therapy manufacturing capacity for BMS's CAR-T franchise.
scanx.trade · +7 outlets
Trump order fast-tracks psychedelic therapies; Compass stock jumps
The executive action signals a lighter regulatory path for psychedelic-based treatments.
Stocktwits
Boehringer backs Zealand Pharma's obesity candidate despite disappointing data
The partner's public support aims to steady confidence in the program after a weak phase 3 result.
medwatch.com · +1 outlets