Caribou Biosciences to shut down, halt CAR-T work after failing to raise late-stage funding
The Jennifer Doudna-co-founded company could not secure money to fund a late-stage trial of its off-the-shelf lymphoma CAR-T therapy and will pursue strategic a
STAT · +10 outlets
Dutch court bars Merck from selling subcutaneous Keytruda in several European countries
The ruling in a patent fight with Halozyme halts manufacturing and marketing of Merck's new subcutaneous Keytruda formulation in parts of Europe.
STAT · +5 outlets
PhRMA sues Trump administration over Medicare drug pricing pilot tied to foreign prices
The brand drug industry's main trade group is challenging a model that would tie Medicare drug prices to those in peer countries.
STAT · +6 outlets
FDA approves Fayuvi, first gene therapy for Sanfilippo Syndrome Type A
The approval marks the first gene therapy cleared for the rare lysosomal storage disorder.
Denkstrom · +14 outlets
Forbion raises $2.6 billion in its largest fundraise to date
The European venture firm's new funds are one of the region's largest raises in recent years, a lift for a biotech sector trailing the U.S. and China.
STAT · +11 outlets
FDA approves Tukysa plus trastuzumab and pertuzumab as first-line maintenance for HER2-positive metastatic breast cancer
The regimen becomes the first approved first-line maintenance option for this breast cancer subtype.
Pharmaceutical Executive · +11 outlets
ArriVent stock collapses after Phase 3 lung cancer trial failure
More than half the company's value was wiped out by data that appear to erase its chance to compete with Johnson & Johnson and others.
Biopharmadive · +11 outlets
Optogenetics restores some vision lost to retinitis pigmentosa in small trial
About half of patients in the study regained photosensitivity, showing promise for the optogenetic approach.
STAT · +14 outlets
AbbVie and Genmab's Epkinly scores in frontline DLBCL trial
Better-than-expected results could make the dual-acting drug the new standard in newly diagnosed large B-cell lymphoma, according to one analyst.
Biopharmadive · +9 outlets
Tempus deepens cancer vaccine collaboration with Moderna and Merck
The expanded partnership builds on mRNA-based personalized cancer vaccine work that reported landmark melanoma data earlier in the year.
ABC Money · +2 outlets
Sensible Biotechnologies raises $47M to rethink mRNA manufacturing
The funding targets a new approach to mRNA production for cancer therapy.
European Biotechnology Magazine · +2 outlets
Atsena's Lighthouse gene therapy shows efficacy in eye disease readout
The gene therapy produced encouraging results in an inherited retinal disease study.
Fierce Biotech · +1 outlets
Rocket Pharma sets 2028 BLA goal for Danon disease gene therapy RP-A501
The company outlined an FDA-aligned pivotal Phase 2 trial and updated clinical findings for its Danon disease gene therapy.
Genome Web · +3 outlets
Nobel Prize in chemistry awarded for 'mirror image' molecule research
Henri B. Kagan and Kenso Soai won for research on chirality with implications for pharmacology.
STAT · +13 outlets
Patrick Soon-Shiong leads $75 million round for Multiply Labs
The AI-focused biotech designs cancer drugs and raised the round led by the billionaire physician.
Billionaires.Africa · +6 outlets
GE HealthCare to acquire Sofie Biosciences for $945M
The deal expands GE HealthCare's radiopharmaceutical capabilities for PET imaging.
Biopharmadive · +14 outlets
MimiVax cancer vaccine fails Phase 2 glioblastoma study
The CEO still called the data 'inspiring' despite the trial miss in glioblastoma.
Fierce Biotech · +1 outlets
Lilly's Jaypirca approved as first-line CLL therapy
The BTK inhibitor gains a first-line indication for chronic lymphocytic leukemia.
STAT