Novartis signs deal worth up to $7.8B with China's Abogen for mRNA-encoded T-cell engager
The licensing and option agreement covers ABO2203, an mRNA-encoded CD19xCD3 T-cell engager for autoimmune diseases, extending big pharma's run of China biotech
BioPharm International · +9 outlets
FDA approves Lilly's Jaypirca for first-line chronic lymphocytic leukemia
The clearance expands the BTK inhibitor into newly diagnosed CLL patients, a larger and more competitive treatment setting.
Fierce Pharma · +11 outlets
Ebola outbreak in Congo passes 4,000 deaths as treatment center burned down
Authorities are struggling to contain what has become the fastest-growing Ebola outbreak on record.
STAT · +13 outlets
AstraZeneca and Daiichi Sankyo add Datroway to cancer collaboration with Summit Therapeutics
The expanded clinical collaboration will test the antibody-drug conjugate in combination regimens alongside Summit's investigational cancer drug.
The Pharma Letter · +12 outlets
Merck signs $2.13B deal with Chinese biotech for experimental cancer drug
The pact adds to a wave of Western pharma licensing deals with Chinese drug developers.
ROI-NJ · +3 outlets
Novo Nordisk bets on Hengrui's weight loss pill in $2.6B deal
The oral obesity asset deal deepens Novo's ties to Chinese drugmakers as competition in weight loss intensifies.
Drug Discovery News · +10 outlets
Lilly launches LillyDirect DTC delivery in Australia, bypassing pharmacies
The direct-to-consumer model for Mounjaro delivery has drawn objections from Australian doctors and pharmacists.
STAT · +2 outlets
FDA launches clinical trial modernization office within CDER
The new office is part of federal efforts to speed drug development as competition from China grows.
Biopharmadive · +14 outlets
Sanofi and Regeneron expand alliance with $1B upfront to find next Dupixent
The two companies will develop long-acting antibody drugs targeting the same pathways as their blockbuster anti-inflammatory drug.
Biopharmadive · +13 outlets
HHS begins programs aimed at accelerating clinical trials amid China competition
The department is funding innovative proposals and weighing an end to the traditional phased clinical trial system.
Biopharmadive · +2 outlets
FDA approves Sanfilippo syndrome gene therapy for childhood dementia
The gene therapy offers the first approved treatment option for the rare neurodegenerative disorder.
European Medical Journal · +14 outlets
Pfizer's eczema drug clears skin in mid-stage trial
Results are competitive with Dupixent and Ebglyss, though analysts question the drug's differentiation in a crowded market.
Biopharmadive · +12 outlets
Novo Nordisk data at European obesity meeting, Lilly's amylin-Zepbound combination impresses
The scientific meeting highlighted amylin combination data, continued weight loss after switching to oral therapy, and competitors' pipeline glimpses.
Biopharmadive · +3 outlets
Lilly ends Foghorn Therapeutics cancer drug partnership after trial disappointment
The pharma giant cut the collaboration after the cancer drug failed to perform in testing, sending Foghorn shares lower.
Biopharmadive · +10 outlets
Study examines whether mRNA Covid vaccines can boost cancer treatment
Researchers reported a link between mRNA vaccine exposure and cancer treatment response, fueling interest in mRNA cancer vaccines.
Business Today · +13 outlets
FDA approves first sirolimus drug-coated balloon
The approval marks the first drug-coated balloon using sirolimus rather than a metal stent-based approach.
Moneycontrol.com · +14 outlets
FDA approves Elevar's Lyrfigtu as first FGFR2 inhibitor for advanced bile duct cancer
The targeted therapy is the first approved FGFR2 inhibitor for the rare biliary tract cancer.
geneonline.com · +1 outlets
Huntington's gene therapy appears to slow functional decline at four years but misses main endpoint
UniQure's gene therapy showed signals of benefit on daily function even as its primary score fell short of statistical significance.
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